Comparative assessment of seven surgical procedures in Carpal Tunnel Syndrome: a network meta-analysis empowering physician-patient decision-making.

ABSTRACT: Carpal Tunnel Syndrome (CTS) is a common peripheral nerve entrapment disorder with a high global burden. Various surgical techniques have been developed to optimize symptom relief and minimize postoperative morbidity. This network meta-analysis (NMA) aimed to compare the relative efficacy and safety of different carpal tunnel release (CTR) procedures. We conducted a systematic review and NMA of randomized controlled trials (RCTs) comparing surgical CTR techniques. Outcomes included symptom severity, pain scores, functional status, patient-reported outcomes, operative time, and adverse events. Data were synthesized using the frequentist approach with the netmeta package in R. Confidence in network estimates was evaluated using the CINeMA framework. Thirty-two RCTs comprising 2,916 patients

SUBMITTER: Elrosasy A 

PROVIDER: S-EPMC12141404 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature