RNA-sequencing Analysis of Hybrid Females Reveals a Dominance of Expression of Alleles From Outcrossing Species Over Those From Selfing Species.

ABSTRACT: The sister species Caenorhabditis briggsae and Caenorhabditis nigoni are the first Caenorhabditis nematode pair known to produce viable F1 hybrids, making them an ideal model for speciation study. Male F1 hybrids are lethal or sterile depending on the parent of origin, while F1 females, though viable, exhibit distinct phenotypes in fecundity and viability. Besides, both female hybrids could mate with C. nigoni males to produce viable progeny but experience hybrid breakdown when crossed with C. briggsae males. The molecular mechanisms driving these phenotype variations in F1 females remain unknown. Here, we analyzed the transcriptomes of F1 female hybrids from both crossing directions to examine whether a parent-specific haplotype dominates gene expression in the hybrids and to explore the

SUBMITTER: Shao Y 

PROVIDER: S-EPMC12142003 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature