Identification of maize genes that condition early systemic infection of sugarcane mosaic virus through single-cell transcriptomics.

ABSTRACT: During the early systemic infection of plant pathogens, individual cells can harbor pathogens at various stages of infection, ranging from absent to abundant. Consequently, gene expression levels within these cells in response to the pathogens exhibit significant variability. These variations are pivotal in determining pathogenicity or susceptibility, yet they remain largely unexplored and poorly understood. Sugarcane mosaic virus (SCMV) is a representative member of the monocot-infecting potyviruses with a polyadenylated RNA genome, which can be captured by single-cell RNA sequencing (scRNA-seq). Here, we performed scRNA-seq on SCMV-infected maize leaves during early systemic infection (prior to symptom manifestation) to investigate the co-variation patterns between viral accumulation and

SUBMITTER: Chen X 

PROVIDER: S-EPMC12143147 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature