Long-term nonsteroidal anti-inflammatory drug use is associated with rotator cuff tears in adult patients.

ABSTRACT:

Background

To determine if long-term nonsteroidal anti-inflammatory drug (NSAID) is associated with rotator cuff tears (RCTs) in an adult population.

Methods

A retrospective study using a national database was performed. All patients with a diagnosis of long-term NSAID use with active records for at least 1 year or 2 years were identified. These patients were matched 1:1 to controls without NSAID use based on age, gender, and Charlson comorbidity index. Rates of new rotator cuff tendon tears were compared. Subgroup analyses in the following age ranges for each sex were done: 35-45, 46-55, 56-65, and 66-75.

Results

Out of 499,240 patients with chronic NSAID use, 10,180 patients sustained a RCT compared to 7471 of the control patients (2.04% vs. 1.50%, respectively; odd

SUBMITTER: Tummala SV 

PROVIDER: S-EPMC12145042 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature