Nettle supplementation improves antioxidant status and modulates inflammatory response by altering lysophosphatidylcholines and enterolactone metabolism in dairy cows.

ABSTRACT: Nettle is not only a nutrient-rich forage but also possesses the potential to act as a nutritional and physiological regulator. This study investigated the effects of supplementing nettle hay into the total mixed rations (TMR) on milk yield, milk composition, antioxidant capacity, immune function, and plasma metabolome in dairy cows. Twenty multiparous Holstein cows with similar days in milk (102 ± 8 d), milk production (39 ± 3 kg/d), milk fat (3.78 ± 0.55%), and milk protein (3.24 ± 0.28%) were randomly assigned to two dietary treatments: a control group (AH group, n = 10) receiving a TMR with 10.5% alfalfa hay and a nettle group (NH group, n = 10) receiving a TMR with 10.5% nettle hay. The experiment lasted for 80 d, including a 20 d pre-feeding period. Milk yield and overa

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC12145696 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature