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Disintegration of Staphylococcus epidermidis biofilms under glucose-limiting conditions depends on the activity of the alternative sigma factor sigmaB.

ABSTRACT: To evaluate the role of the polysaccharide intercellular adhesin as an energy-storage molecule, we investigated the effect of nutrient limitation on S. epidermidis biofilms. The stability of established biofilms depends on sigma(B) activity; however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely.

SUBMITTER: Jager S 

PROVIDER: S-EPMC1214654 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature

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Disintegration of Staphylococcus epidermidis biofilms under glucose-limiting conditions depends on the activity of the alternative sigma factor sigmaB.

Jäger Sebastian S   Mack Dietrich D   Rohde Holger H   Horstkotte Matthias A MA   Knobloch Johannes K-M JK  

Applied and environmental microbiology 20050901 9

To evaluate the role of the polysaccharide intercellular adhesin as an energy-storage molecule, we investigated the effect of nutrient limitation on S. epidermidis biofilms. The stability of established biofilms depends on sigma(B) activity; however, the slow decay of biofilms under conditions of nutrient limitation reveal its use as an energy-storage molecule to be unlikely. ...[more]

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