Longitudinal associations between birth-to-six cortical growth and childhood neurocognitive function.

ABSTRACT: The human cortex undergoes immense change in the first years of life, doubling in thickness within the first year and evidencing the greatest change within the first 5 y. While substantial research has identified the early postnatal period as a sensitive period in cortical development, research to date lacks the temporal resolution necessary to identify which aspects of cortical change predict later neural and cognitive function. This study leveraged a rich longitudinal dataset of cortical thickness in 50 children who were scanned up to 11 times between birth and 6 y. We used nonlinear multilevel modeling to explore patterns of cortical change across the brain during this period and distinguish whether different phases of change would predict performance and brain activation during a worki

SUBMITTER: Davis MM 

PROVIDER: S-EPMC12146774 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature