Genomic diversity of clinically relevant bacterial pathogens from an acute care hospital in Suva, Fiji.

ABSTRACT:

Objectives

Antimicrobial resistance (AMR) is a global health threat, with third-generation cephalosporin-resistant (3GCR) and carbapenem-resistant infections of particular concern. There is currently a lack of genomic data on AMR organisms in the Pacific region.

Methods

We aimed to address this gap by examining the genetic diversity of a collection of 788 Gram-negative and Gram-positive clinical isolates collected between July 2020 and October 2022 from a single hospital in Suva, Fiji. We sampled sensitive and resistant isolates, focusing on 3GCR and carbapenem-resistant Gram-negatives, and methicillin-resistant Staphylococcus and vancomycin-resistant Enterococcus.

Results

We detected 29 distinct species across 12 different genera. Amongst Gram-negative

SUBMITTER: Hawkey J 

PROVIDER: S-EPMC12147017 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature