Impact of prehospital extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest on survival with good neurological function: a systematic review and meta-analysis.

ABSTRACT:

Aim

Prehospital extracorporeal cardiopulmonary resuscitation (ECPR) has been proposed to reduce delays in ECPR delivery in refractory out-of-hospital cardiac arrests (OHCA) and improve outcomes. Our aim was to synthesize the literature on outcomes of prehospital ECPR in OHCA, focusing on low-flow times (emergency call to extracorporeal blood flow) and survival with good neurological function, comparing them to in-hospital ECPR when possible.

Methods

We conducted a systematic review and meta-analysis of studies reporting outcomes in adult OHCA patients treated with prehospital ECPR. Searches spanned seven databases and relevant grey literature (last updated January 21, 2025). Eligible studies included ≥ 5 patients. The primary outcome was survival with good neurologica

SUBMITTER: Leroux L 

PROVIDER: S-EPMC12148607 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature