Monte Carlo modeling of radiation dose from radiation therapy with superficial x-rays.

ABSTRACT:

Introduction

Superficial x-rays (50-100 kVp) are used for treating non-melanoma skin cancer and intraoperative radiation therapy (IORT). At these energies, the photoelectric effect significantly increases absorbed dose to bone compared to soft tissue.

Methods

We used EGSnrc MC simulations to investigate bone dose enhancement during radiotherapy with the Sensus SRT-100 machine. Simulated beams were validated against laboratory measurements and compared to a commercial treatment planning system (SmART-ATP). Transmission simulations indirectly predicted bone dosage. Simulated beams were utilized as a mock treatment plan from a human cone-beam computed tomography (CBCT) image.

Results

EGSnrc accurately modeled the Sensus SRT-100 beams (100, 70, and 50 kVp) with a root mea

SUBMITTER: Barghash R 

PROVIDER: S-EPMC12148772 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature