Perioperative Intravenous Lidocaine Infusion Therapy as an Adjunct to Multimodal Analgesia for Adolescent Idiopathic Scoliosis Surgical Correction: A Double-Blind Randomized Controlled Trial.

ABSTRACT:

Background

Posterior spinal instrumentation and fusion is a common surgical correction for adolescent idiopathic scoliosis. Preventative multimodal analgesia, including opioids, is required to minimize postoperative pain, but opioids are associated with dose-dependent side effects that may disrupt recovery.

Aims

We hypothesized that the addition of 48-h perioperative intravenous lidocaine therapy to a multimodal analgesia regimen would reduce morphine utilization.

Method

We conducted a double-blinded randomized controlled trial in 10-19 years old, ASA I-III, undergoing single-stage scoliosis correction. Participants were randomly allocated to the Intervention group (intravenous lidocaine 1 mg kg^-1 bolus at anesthesia start, followed by 2 mg kg^-1 

SUBMITTER: Luo J 

PROVIDER: S-EPMC12149479 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature