Rapid diagnosis of ocular viral infections via single-virus detection using solid-state nanopore: A diagnostic evaluation study.

ABSTRACT: Rapid and precise identification and discrimination of causative pathogens are required in the treatment of infectious diseases. Quantitative real-time PCR is used to detect and identify infectious viruses before treatment. Although it is an established modality, results take several hours, even in well-equipped hospitals. It is difficult to simultaneously detect many pathogen types because only a single-virus genome can be amplified per PCR. Recently, an AI-based nanopore machine has been used to identify individual viruses based on electrical conductivity. Here, we recognized a single virus using an AI-based detection system and successfully identified viral particles in clinical samples without the need for any prior treatment. We used a nanopore detector and discriminated among viruses

SUBMITTER: Hashida N 

PROVIDER: S-EPMC12150286 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature