Late gadolinium-enhanced cardiovascular magnetic resonance for predicting left ventricular reverse remodeling in dilated cardiomyopathy: A comprehensive review and meta-analysis.

ABSTRACT:

Background

There is currently a lack of evidence regarding the significance of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) in predicting left ventricular (LV) reverse remodeling (RR) in pooled data. This study aimed to evaluate the predictive value of the presence and extent of LGE for LVRR in patients with dilated cardiomyopathy (DCM).

Methods

Systematic searches were conducted in PubMed, Embase, Cochrane Library, and ClinicalTrials.gov from database inception to May 21, 2024. We estimated the overall effect sizes using the Mantel-Haenszel random-effects model. Subgroup analyses, meta-regression, and sensitivity analyses were performed to investigate potential sources of heterogeneity among studies.

Results

A total of 1141 patients (LGE prev

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12151184 | biostudies-literature | 2025 Summer

REPOSITORIES: biostudies-literature