Characterization and whole-genome sequencing data of a highly pathogenic group B <i>Streptococcus</i> strain related to stillbirth.

ABSTRACT: Group B Streptococcus (GBS), a primary pathogen associated with perinatal and maternal infections, can lead to severe complications such as preterm birth, miscarriage, and stillbirth. In this study, we report the isolation of GBS from the blood of a patient with sepsis who had delivered a stillborn. Genome sequencing was performed using the Pacbio Sequel II and DNBSEQ platform. GBS-B4009 contained a circular chromosome with a total length of 2,277,992 bp and the GC content of the chromosome was determined to be 35.97 %. The whole genome sequence contained 2256 predicted coding sequences, including 21 ribosomal RNA (rRNA), 81 transfer RNA (tRNA), and 24 small RNAs (sRNAs). Additionally, we also isolated GBS from two additional pregnant women: GBS-M14, isolated from the pregnant woman

SUBMITTER: Wang J 

PROVIDER: S-EPMC12151202 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature