Clinical study outcomes in IgA nephropathy: A systematic literature review and narrative synthesis.

ABSTRACT:

Introduction

IgA nephropathy (IgAN) is an inflammatory kidney disease which, if left untreated, often progresses to kidney failure (KF). This systematic literature review identifies, collates, summarizes, and assesses the quality of clinical trial data describing the efficacy of therapies used for IgAN.

Methods

Ovid Embase, PubMed, CENTRAL, and the Cochrane database of systematic reviews were searched on October 18th, 2021, and updated on December 12th, 2023. Electronic searches were supplemented with manual searches of key conferences, clinical trial registries, and bibliography screening. PRISMA and Cochrane guidelines were followed.

Results

A total of 6710 references were identified (electronic and manual searches), of which 6483 were excluded. This resulted in 254

SUBMITTER: Jeyabalan A 

PROVIDER: S-EPMC12151485 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature