Restoration of gut microbiota with a specific synbiotic-containing infant formula in healthy Chinese infants born by cesarean section.

ABSTRACT:

Background

Birth by cesarean section (C-section) is associated with a delayed colonization of bifidobacteria and Bacteroidota species with potential negative health consequences. Previously, an infant formula with a synbiotic mixture of short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (scGOS/lcFOS [9:1]) and Bifidobacterium breve M-16V was found to restore the timely colonization of bifidobacteria in C-section born infants. In this study, we investigated the effect of this synbiotic mixture on gut microbiota development in C-section and vaginally-born infants participating in a growth equivalence trial (NCT03520764).

Methods

Healthy, fully formula-fed Chinese infants were randomized to receive a partially hydrolyzed whey-based protein formula with

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12151850 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature