Hearing Function in Spinal and Bulbar Muscular Atrophy (SBMA): A Case Control Study From a Tertiary Referral Center.

ABSTRACT:

Background

Expanding on earlier findings of auditory involvement from two small-scale studies, we conducted a comprehensive evaluation of hearing levels in a larger cohort of SBMA patients.

Methods

Thirty-six SBMA patients and 36 age-matched male controls without risk factors for hearing loss underwent a comprehensive audiological assessment, including pure-tone audiometry at 250, 500, 1000, 2000, 4000, and 8000 Hz frequencies, using both air and bone conduction. The pure-tone average (PTA) was calculated as the mean threshold at 500, 1000, 2000, and 4000 Hz. A correlation analysis was performed to evaluate the relationship between patients' audiological features and clinical characteristics, including motor disability, as measured by the SBMA functional rating scale (SBMAFR

SUBMITTER: Blasi L 

PROVIDER: S-EPMC12152368 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature