Mining peptides for mining solutions: evaluation of calcium-binding peptides for rare earth element separations.

ABSTRACT: Rare earth elements (REEs), which include the 15 lanthanides plus scandium and yttrium, are critical components commonly used in permanent magnets and play a significant role in electronics and green energy technologies. Due to the similarities of these ions, conventional separation processes are chemically- and energy-intensive and generate large quantities of waste. The lanthanides share physical and chemical similarities with calcium ions, which allow REEs to replace calcium in calcium-binding peptides and proteins. In this study, we conducted a bioinformatic search to identify calcium-binding peptides with high affinity to bind and separate REEs. Seven unique domains representing different calcium-binding geometries were selected for evaluation. The results revealed a strong correlatio

SUBMITTER: Khoury FF 

PROVIDER: S-EPMC12152738 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature