Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats.

ABSTRACT: Cashmere goats are excellent livestock breeds known for producing high-quality cashmere fibers from secondary hair follicles. In this study, we aimed to explore the key RNA molecules responsible for the differences in cashmere quality between Jiangnan cashmere goats (JNCG) and Changthangi pashmina goats (CPG). Skin transcriptomic data from the anagen, catagen, and telogen stages of hair follicle growth were retrieved from the SRA database for both JNCG and CPG. Bioinformatics analyses were conducted to identify key molecular differences underlying the variation in cashmere fiber quality. The results showed that there were 4,942 differentially expressed genes (DEGs) between JNCG and CPG through differential analysis, and the DEGs were mainly enriched in PI3K-Akt signaling pathway, Thermogen

SUBMITTER: Gong G 

PROVIDER: S-EPMC12153449 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature