Chevreul: An R Bioconductor Package for Exploratory Analysis of Full-Length Single Cell Sequencing.

ABSTRACT: Chevreul is an open-source R Bioconductor package and interactive R Shiny app for processing and visualization of single cell RNA sequencing (scRNA-seq) data. It differs from other scRNA-seq analysis packages in its ease of use, its capacity to analyze full-length RNA sequencing data for exon coverage and transcript isoform inference, and its support for batch correction. Chevreul enables exploratory analysis of scRNA-seq data using Bioconductor SingleCellExperiment or Seurat objects. Simple processing functions with sensible default settings enable batch integration, quality control filtering, read count normalization and transformation, dimensionality reduction, clustering at a range of resolutions, and cluster marker gene identification. Processed data can be visualized in an interactiv

SUBMITTER: Stachelek K 

PROVIDER: S-EPMC12154678 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature