Optimizing TB policies using the global TB portfolio model: an economic analysis.

ABSTRACT:

Rationale

Tuberculosis (TB) remains a global health crisis, disproportionately affecting low- and middle-income countries. Strategic resource allocation is essential to achieving the WHO End TB targets. Existing TB costing tools have limitations in conducting global analyses, prompting the development of a novel model tailored to address these gaps.

Methods

We developed a new, open-source TB costing model that simulates detailed TB care cascades comprising steps of screening, diagnosis, treatment, and prevention for those eligible - according to WHO guidelines for 20 distinct population groups. These include 10 groups each from patient-initiated and provider-initiated pathways, capturing variations in pulmonary status, age, HIV/ART status, and drug sensitivity. The model cap

SUBMITTER: Satyanarayana S 

PROVIDER: S-EPMC12155012 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature