The Association between Multiple Environmental Exposures and Symptoms of Generalized Anxiety Disorder in a Prospective, US-Based Cohort Study.

ABSTRACT:

Background

Emerging evidence has implicated built and natural environmental exposures in the etiology and exacerbation of anxiety symptoms.

Objectives

Our objective was to assess individual and joint associations between neighborhood socioeconomic status (nSES), walkability, greenness, fine particulate matter (PM2.5), nitrogen dioxide (NO2), and temperature and generalized anxiety disorder (GAD) symptoms.

Methods

We included 81,897 participants of the Nurses' Health Study II. GAD symptoms were measured in 2013 and 2017 using the seven-item Generalized Anxiety Disorder scale (GAD-7). Walkability and nSES z-scores were calculated at the census tract level. Summer and annual average greenness were measured using Normalized Difference Vegetation Index (NDVI) at 270

SUBMITTER: Mehta UV 

PROVIDER: S-EPMC12156197 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature