Geospatial analysis of leptospirosis clusters and risk factors in two provinces of the Dominican Republic.

ABSTRACT:

Background

Drivers of leptospirosis transmission can vary across regions, leading to spatial clustering of infections. This study aims to identify clusters of leptospirosis seroprevalence in the Dominican Republic (DR) and factors associated with high-risk areas.

Methodology/principal findings

We analysed data from two provinces, Espaillat and San Pedro de Macoris (SPM), obtained on a national survey conducted in 2021 (n = 2,078). Samples were tested by microscopic agglutination testing (MAT) to detect leptospirosis antibodies. We used flexible spatial scan statistics to locate significant clusters for seropositive individuals (all serogroups combined) in each province and calculated risk ratios (RR) at the household and community level. Environmental and sociodemographic ri

SUBMITTER: Martin BM 

PROVIDER: S-EPMC12157080 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature