Global hotspots and trends in pre-metastatic niche research: a bibliometric analysis(2005-2024).

ABSTRACT:

Background

The pre-metastatic niche (PMN) represents the microenvironment established in target organs before primary tumor metastasis, playing a crucial role in organ-specific metastasis. Understanding and preventing PMN formation holds promise for enhancing immunotherapy efficacy and reducing cancer-related mortality. Despite the significance of this field, a comprehensive bibliometric analysis is lacking. This study aims to identify global research trends and hotspots in PMN through a systematic bibliometric evaluation, providing a foundation for future advancements in this field.

Methods

Publications related to PMN research from 2005 to 2024 were retrieved from the Web of Science Core Collection database. Bibliometric analyses and visualizations were conducted using VOSv

SUBMITTER: Cheng M 

PROVIDER: S-EPMC12159010 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature