Performances of Malaria PfHRP2 and the Combined PfHRP2/pLDH Based Rapid Diagnostic Tests among Children Under Five Years of Age in a High Seasonal Malaria Transmission Area in Burkina Faso.

ABSTRACT:

Purpose

Despite countrywide seasonal malaria chemoprevention (SMC) in Burkina Faso, malaria remains high among under-five year children during peak transmission season, questioning about SMC effectiveness and diagnostic tools accuracy.

Methods

This study assessed the performance of SD-Bioline malaria rapid diagnostic test (RDT) P.f^® (PfHRP2) alongside combined SD-Bioline malaria RDT P.f^® (HRP2/pLDH) and light microscopy (LM) against varATS quantitative polymerase chain reaction (qPCR) as reference, among SMC-aged children in high seasonal malaria transmission setting in Burkina Faso. A two-year longitudinal study (March 2019-March 2021) conducted in Nanoro health district screened 995 suspected malaria cases. Diagnostic performances of PfHRP2-based RDT

SUBMITTER: Ouedraogo DF 

PROVIDER: S-EPMC12159090 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature