Altered autonomic cardiovascular function in adults with persisting post-concussive symptoms and exercise intolerance.

ABSTRACT: Alterations in autonomic cardiovascular function may result following mild traumatic brain injury (mTBI), but there is a lack of data evaluating autonomic function in adults with persisting post-concussive symptoms (PPCS). We collected resting measures of heart rate (HR), heart rate variability (HRV), blood pressure (BP) and cardiac baroreceptor sensitivity in 50 adults with PPCS (42.8 (11.0) years; 24.5 (14.2) months post-injury; 74% female) and 50 age/sex-matched controls (43.0 (11.1) years; 74% female) with no lifetime mTBI history. HR and BP data were collected for ≥4 min when seated and standing. Between-group differences (PPCS vs. control) were analyzed using linear regression. In the seated posture, participants with PPCS had significantly lower HRV than controls, specifically RMSSD

SUBMITTER: Mercier LJ 

PROVIDER: S-EPMC12159307 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature