Molecular responses of chicken embryos to maternal heat stress through DNA methylation and gene expression: a pilot study.

ABSTRACT: Climate change, with its repercussions on agriculture, is one of the most important adaptation challenges for livestock production. Poultry production is a major source of proteins for human consumption all over the world. With a growing human population, improving poultry's adaptation to environmental constraints becomes critical. Extensive evidence highlights the influence of environmental variations on epigenetic modifications. The aim of this paper is therefore to explore chickens' molecular response to maternal heat stress. We employed Reduced Representation Bisulfite Sequencing to generate genome-wide single-base resolution DNA methylation profiling and RNA sequencing to profile the transcriptome of the brains of embryos hatched from dams reared under either heat stress (32°C) or the

SUBMITTER: Karami K 

PROVIDER: S-EPMC12159801 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature