Quantitative Analysis of 3D Anatomy to Inform Planning of Ductal Arteriosus Stenting.

ABSTRACT:

Background

Ductus arteriosus stenting (DAS) is used to palliate infants with ductal-dependent pulmonary blood flow (DD-PBF), however patent ductus arteriosus (PDA) anatomy can be complex and heterogenous.

Aims

We developed custom, open-source software to model and quantify PDA anatomy.

Methods

We retrospectively identified 33 neonates with DD-PBF with a CTA before DAS. A novel custom workflow was implemented in 3D Slicer and SlicerHeart to semi-automatically extract centerlines of the course of the PDA and surrounding vessels. 3D ductal length, diameter, curvature and tortuosity were automatically calculated (3D automatic) and compared to manually adjusted 3D measurements (3D semi-automatic), and manual measurements of PDA dimensions in 2D projectional angiograms befo

SUBMITTER: Gupta M 

PROVIDER: S-EPMC12162213 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature