Impact of white matter lesions on associations between prehospital blood pressure and outcomes in spontaneous intracerebral hemorrhage.

ABSTRACT:

Introduction

There are concerns about the safety of intensive blood pressure (BP) lowering in intracerebral hemorrhage (ICH) patients with white matter lesions (WML). We explored the impact of WML on associations between i) prehospital BP, and ii) BP change, and outcomes in acute, spontaneous ICH.

Patients and methods

This retrospective study included consecutive patients with acute spontaneous ICH, admitted 2011-2020. WML on non-contrast computed tomography were categorized as none-to-mild (0-1) or moderate-to-severe (2-3) on the Fazekas scale. The first systolic BP (SBP) and mean arterial pressure (MAP) from the ambulance and admission, and absolute BP change between these time points, were collected. The outcomes were in-hospital mortality, mortality at 180 days, modified

SUBMITTER: Larsen KT 

PROVIDER: S-EPMC12162525 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature