Triglyceride-glucose index is associated with lupus nephritis and gender disparity in systemic lupus erythematosus patients.

ABSTRACT:

Objective

Recent studies investigated that triglyceride glucose (TyG) index and triglyceride (TG) are associated with an elevated likelihood of developing and worsening chronic kidney disease (CKD). We aimed to evaluate the correlation between the TyG index and TG with lupus nephritis (LN), respectively, and explore its value in monitoring LN.

Methods

1,192 Systemic Lupus Erythematosus (SLE) patients were involved in this cross-sectional investigation. The presence or absence of LN was used to divide the individuals involved into two distinct categories. Multivariate logistic regression, restricted cubic spline, and subgroup analyses were applied to explore the connection between the TyG index and TG with LN, respectively.

Results

According to the study, the TyG index

SUBMITTER: Lin S 

PROVIDER: S-EPMC12162929 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature