Improvement on mitochondrial energy metabolism of <i>Codonopsis pilosula (Franch.) Nannf.</i> polysaccharide.

ABSTRACT:

Ethnopharmacological relevance

Codonopsis pilosula (Franch.) Nannf. (CP) is one of the most popular Qi-invigorating herbal medicines and has been extensively used to promote health and vitality in China for a long time. Codonopsis pilosula (Franch.) Nannf. polysaccharide (CPP) is the principal active components of CP, which is considered as the reason for CP widespread application. However, it has not been revealed that CPP exert a Qi-invigoration effect by protecting mitochondria and/or improving mitochondrial function in the existing traditional Chinese medicine theories.

Aim of the study

We extracted CPP from C. pilosula and investigated the effects of CPP on energy metabolism and mitochondrial protection.

Methods

Based on the mice chronic hypo

SUBMITTER: Li H 

PROVIDER: S-EPMC12162984 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature