Long-Term Effectiveness Associated With Fecal Immunochemical Testing for Early-Age Screening.

ABSTRACT:

Importance

The rising incidence of young-onset colorectal cancer (CRC) has prompted health policymakers to consider lowering the recommended starting age for screening. However, population-based evidence supporting the long-term effectiveness of early-age screening remains limited.

Objective

To evaluate whether initiating fecal immunochemical test (FIT) screening at ages 40 to 49 years, rather than at the currently recommended age of 50 years, reduces CRC incidence and mortality.

Design, setting, and participants

This study analyzed a community-based screening cohort of Taiwanese residents aged 40 to 49 years, categorized into 4 subcohorts based on participation in early screening (age 40 to 49 years) and continuation of nationwide regular screening (50 years and olde

SUBMITTER: Chiu HM 

PROVIDER: S-EPMC12163714 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature