Molecular characterization of clinical non-typhoidal <i>Salmonella</i> isolates shows high antimicrobial resistance burden in Jiangsu, China.

ABSTRACT: Non-typhoidal Salmonella (NTS) poses a significant global health burden due to its association with gastroenteritis and rising antimicrobial resistance (AMR). This study conducted a genomic analysis of 62 Salmonella isolates from outpatient cases in Jiangsu, China, to monitor the epidemiological characteristics of NTS, including genetic diversity, AMR profiles, and resistance transmission mechanisms 18 serovars and 21 sequence types (STs) were identified by whole genome sequencing, with S. enteritidis (27.42%) and S. typhimurium (19.35%) predominating. 61 resistance genes from ten different antimicrobial categories were found by genotypic AMR screening. 90.32% of isolates had β-lactam resistance genes, indicating a high frequency of extended-spectrum β-la

SUBMITTER: Cao H 

PROVIDER: S-EPMC12164032 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature