Implementation of ultra-hypofractionated radiotherapy for breast cancer in the Netherlands in 2020-2023, using registry data and questionnaires.

ABSTRACT:

Background

This study investigated the implementation of ultra-hypofractionated radiotherapy (i.e. 5 fractions) in DCIS and early-stage breast cancer, factors associated with its use, and variation across radiotherapy institutes.

Methods

Registry and questionnaire data were used. Registry data included data from the Netherlands Cancer Registry and the NABON Breast Cancer Audit-Radiotherapy (NBCA-R). Women eligible for 5 fractions were included. Trends and variation were visualised using trendlines and case-mix adjusted boxplots. Logistic regression was applied to investigate which factors were associated with the use of 5 fractions. In April 2024 a questionnaire was distributed among radiotherapy institutes to identify facilitators and barriers for implementation.

Results

SUBMITTER: Eijkelboom AH 

PROVIDER: S-EPMC12164123 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature