Dietary grape pomace ameliorates intestinal damage and oxidative stress by modulating MAPK-Nrf2/ARE pathways in coccidia-challenged broilers (Gallus gallus).

ABSTRACT: Grape pomace (GP) is an agricultural byproduct rich in bioactive compounds with antimicrobial, antioxidant, and immunomodulatory properties that have proven to have strong antioxidant and immunomodulatory properties in chickens. As a part of a defense mechanism, coccidiosis initiates oxidative bursts, generating large amounts of free radical species that negatively affect the gut health of chickens. This study aimed to evaluate the effect of dietary inclusion of GP in broilers infected with coccidiosis on physiological and molecular markers of gut health, immune response, and oxidative status. A total of 120 male broiler chickens were randomly assigned to one of the four treatments. The four treatment groups were i) non-challenged control without any dietary feed additives (NCC), ii) chall

SUBMITTER: Sharma MK 

PROVIDER: S-EPMC12164180 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature