Transcriptomic analysis of the liver, jejunum, and uterus in different production stages of laying hens.

ABSTRACT: Egg production in laying hens is related to very complex and elaborate processes involving the cooperation of various tissues. Laying hens undergo this complicated production process in different production stages during overall laying periods. However, many previous studies have focused on a single tissue or specific production stage. Thus, we compared multi-tissue transcriptome profiles across different production stages using RNA-seq to understand which overall metabolic changes occur in laying hens as the stage progresses. Laying hens at three distinct production stages of early-phase (EP, 30 wk of age), mid-phase (MP, 46 wk of age), and late-phase (LP, 60 wk of age) were used to analyze transcriptomic changes for the liver, jejunum, and uterus tissues. Weighted gene co-expression netw

SUBMITTER: Han GP 

PROVIDER: S-EPMC12164196 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature