Evaluation of MRI characterisation of histopathologically matched lymph nodes and other mesorectal nodal structures in rectal cancer.

ABSTRACT:

Purpose

To evaluate current MRI-based criteria for malignancy in mesorectal nodal structures in rectal cancer.

Method

Mesorectal nodal structures identified on baseline MRI as lymph nodes were anatomically compared to their corresponding structures histopathologically, reported as lymph nodes, tumour deposits or extramural venous invasion. All anatomically matched nodal structures from patients with primary surgery and all malignant nodal structures from patients with neoadjuvant treatment were included. Mixed-effects logistic regression models were used to evaluate the morphological criteria irregular margin, round shape, heterogeneous signal and nodal size, as well as the combined 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus criteria,

SUBMITTER: Rutegard MK 

PROVIDER: S-EPMC12165870 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature