Coronary calcium score and emphysema extent on different CT radiation dose protocols in lung cancer screening.

ABSTRACT:

Objectives

To assess the consistency of automated measurements of coronary artery calcification (CAC) burden and emphysema extent on computed tomography (CT) images acquired with different radiation dose protocols in a lung cancer screening (LCS) population.

Materials and methods

The patient cohort comprised 361 consecutive screenees who underwent a low-dose CT (LDCT) scan and an ultra-low-dose CT (ULDCT) scan at an incident screening round. Exclusion criteria for CAC measurements were software failure and previous history of CVD, including coronary stenting, whereas for emphysema assessment, software failure only. CT images were retrospectively analyzed by a fully automated AI software for CAC scoring, using three predefined Agatston score categories (0-99, 100-399, and ≥ 4

SUBMITTER: Ledda RE 

PROVIDER: S-EPMC12165900 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature