Predictive and prognostic value of the neutrophil-to-lymphocyte ratio for acute kidney injury: a systematic review and meta-analysis.

ABSTRACT: The neutrophil-to-lymphocyte ratio (NLR) has been suggested as a potential biomarker for the prediction and risk stratification of acute kidney injury (AKI), but conflicting results were reported by literature. We therefore conducted a pooled analysis to consolidate available evidence regarding the predictive and prognostic value of NLR in AKI patients. A systematic search was performed in the PubMed/Medline, Embase, and Cochrane Central Register of Controlled Trials (Central) databases from inception to March 2025 for cohort studies investigating the association between NLR and AKI. Quality assessment was performed via the Quality Assessment for Studies of Diagnostic Accuracy (QUADAS-2) tool. The predictive and prognostic value of the NLR for AKI was evaluated via pooled estimates of odds

SUBMITTER: Wei W 

PROVIDER: S-EPMC12165981 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature