Fecal microbiome analysis in patients with metabolic syndrome and type 2 diabetes.

ABSTRACT:

Background

Metabolic syndrome (MS) and type 2 diabetes (T2D) are metabolically related diseases with rising global prevalence and increasingly evident links to the intestinal microbiota. Research suggests that imbalances in microbiota composition may play a crucial role in their pathogenesis. Specific population cohorts, such as the one in Galicia, Spain, offer the opportunity to analyze microbiota patterns within a distinct geographical and genetic context. This study was performed to investigate the relationship between the intestinal microbiota and MS and T2D.

Methods

A cohort of 79 volunteers was analyzed over a 2-year study period. Recruitment posed significant challenges because of strict inclusion criteria (918PTE0540; PCI2018-093284), which required participants to b

SUBMITTER: Sinisterra Loaiza LI 

PROVIDER: S-EPMC12166849 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature