Decoding portal vein pulsatility: hemodynamic determinants in a post-hoc analysis of a prospective observational trial.

ABSTRACT:

Background

The portal vein pulsatility index (PVPI) reflects systemic congestion and is influenced by both volume status and right ventricular (RV) function. The mean systemic filling pressure analogue (Pmsa), derived from a mathematical model, estimates the interaction between stressed blood volume and systemic vascular compliance, serving as surrogate marker of volume status. This post-hoc analysis of an observational trial investigates the combined role of Pmsa and RV function as determinants of PVPI using echocardiography. Fifty-five mechanically ventilated patients with circulatory failure were included within 6 h of ICU admission following elective open-heart surgery. Fluid-tolerant patients (PVPI < 50%) underwent a passive leg raising (PLR) test; fluid-responsive patients su

SUBMITTER: Balan C 

PROVIDER: S-EPMC12167214 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature