Hyperuricemia, gout and the associated comorbidities in China: findings from a prospective study of 0.5 million adults.

ABSTRACT:

Background

Despite the growing prevalence of hyperuricemia and gout, their epidemiology and associated comorbidity burden remains poorly studied in many populations, including China. We aimed to examine the patterns of plasma urate level, prevalence of hyperuricemia, and incidence of gout, and investigate the associations of gout with a range of comorbidities and all-cause mortality in Chinese adults.

Methods

The prospective China Kadoorie Biobank recruited 512,724 adults aged 30-79 years from ten diverse areas in 2004-2008 and measured plasma urate level among 16,817 participants. The incidence of gout and other diseases and deaths were monitored by electronic linkages with registries and hospital records. Cox and logistic regression yielded adjusted HRs and ORs for risks o

SUBMITTER: Im PK 

PROVIDER: S-EPMC12167516 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature