Diverse Genetic Mechanisms Enable Pseudomonas syringae to Rapidly Overcome Effector-Triggered Immunity.

ABSTRACT: Bacterial plant pathogens pose a serious threat to worldwide crop yields and cause widespread food insecurity. One common approach to limit pathogen proliferation on critical crops is to genetically engineer cultivars that harbour resistance genes capable of recognising and responding to critical bacterial virulence factors like type III secreted effectors. Unfortunately, these resistance barriers are often overcome by pathogen evolution within just a few seasons. In this study, we explore the evolutionary mechanisms that enable pathogens to overcome plant resistance by leveraging two Pseudomonas syringae pv. maculicola strains that differ in their ability to cause disease on the model host Arabidopsis thaliana. We first characterise the molecular basis of the adaptation that enabled the P

SUBMITTER: Newfeld J 

PROVIDER: S-EPMC12167760 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature