Stepwise deactivation of gibberellins during rice internode elongation.

ABSTRACT: Bioactive gibberellins (GAs) are a class of plant hormones that regulate various aspects of plant growth and development, and several key GA deactivation enzymes have been identified. In rice, non-13-hydroxylated GAs have been shown to be deactivated via 16α,17-epoxidation by a cytochrome P450 monooxygenase, ELONGATED UPPERMOST INTERNODE (EUI/CYP714D1). Although 16,17-dihydro-16α,17-epoxyGA₄ (16α,17-epoxyGA₄), the product of EUI from bioactive GA₄, has shown weak bioactivity on rice seedlings, how 16α,17-epoxyGAs are further deactivated remains elusive. Here, we identify the EUI2 gene, which regulates internode elongation in rice, using a map-based cloning strategy. EUI2 encodes an epoxide hydrolase that hydrolyzes 16α,17-epoxyGAs to 16,17-dih

SUBMITTER: Ishida T 

PROVIDER: S-EPMC12167944 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature