Phylodynamics for Human Immunodeficiency Virus Prevention: A Miami-Dade County Case Study.

ABSTRACT:

Background

To date, human immunodeficiency virus (HIV) molecular epidemiology has been primarily used to identify clusters of related infections (cluster detection and response) and then address interventions to these clusters. Community groups have raised concern regarding cluster detection and response related to privacy and ethical concerns. Here we demonstrate how an alternative approach to HIV molecular epidemiology can provide public health benefit.

Methods

A limited data set for Miami-Dade County provided by the Florida Department of Health was curated and annotated by neighborhood health district (NBHD) and genetic linkage (using a genetic distance threshold of ≤0.5%) and phylodynamic analyses were performed. Phylodynamic analyses were used to infer viral transmissio

SUBMITTER: Mehta SR 

PROVIDER: S-EPMC12168071 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature