Remodeling of the terpenoid metabolism during prolonged phosphate depletion in the marine diatom Phaeodactylum tricornutum.

ABSTRACT: Terpenoids are a diverse class of naturally occurring organic compounds, which derive from five-carbon isoprene units and play crucial roles in physiology, ecological interactions such as defense mechanisms, or adaptation to environmental stresses. In Phaeodactylum tricornutum, some of the most important isoprenoids are sterols and pigments, derived from precursors of the cytosolic mevalonate and the plastidial methyl-erythritol 4-phosphate pathway, respectively. However, the regulation of isoprenoid metabolism in P. tricornutum has not yet been characterized, presenting a major gap in our understanding of its ecological functions and adaptations. By leveraging metabolic, photosynthetic, and transcriptomic analyses, we characterized the dynamic remodeling of the isoprenoid pathways during

SUBMITTER: Pruckner F 

PROVIDER: S-EPMC12168105 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature