Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke.

ABSTRACT: Acoustic-phonetic perception refers to the ability to perceive and discriminate between speech sounds. Acquired impairment of acoustic-phonetic perception is known historically as 'pure word deafness' and typically follows bilateral lesions of the cortical auditory system. The extent to which this deficit occurs after unilateral left hemisphere damage and the critical left hemisphere areas involved are not well defined. We tested acoustic-phonetic perception in 73 individuals with chronic left hemisphere stroke and performed multivariate lesion-symptom mapping incorporating controls for non-specific task confounds, pure tone hearing loss, response bias and lesion size. Separate analyses examined place of articulation, manner of articulation, voicing and vowel discriminations. Overlap of th

SUBMITTER: Binder JR 

PROVIDER: S-EPMC12168130 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature