An auditory cortical-striatal circuit supports sound-triggered timing to predict future events.

ABSTRACT: A crucial aspect of auditory perception is the ability to use sound cues to predict future events and to time actions accordingly. For example, the sound of an approaching vehicle signals when it is safe to cross the street; distinct smartphone notification sounds reflect a call that needs to be answered within a few seconds, or a text that can be read later. Other animals similarly use sounds to plan, time and execute behaviors such as hunting, evading predation and tending to offspring. However, the neural mechanisms that underlie sound-guided prediction of upcoming salient event timing are not well understood. To address this gap, we employed an appetitive sound-triggered reward time prediction behavior in head-fixed mice. We find that mice trained on this task reliably estimate the tim

SUBMITTER: Suri H 

PROVIDER: S-EPMC12169527 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature