Preventing respiratory illness in cerebral palsy: Results of a pilot randomized controlled trial.

ABSTRACT:

Background

Respiratory illness is consistently the leading cause of death and hospitalization in severe cerebral palsy (CP). Respiratory Exacerbations-Plan for Action and Care Transitions (RE-PACT) is a just-in-time adaptive intervention to prevent respiratory illness in severe CP. RE-PACT combines early illness detection with rapid clinical response to address varying causes of respiratory illness early enough to modify illness trajectory. This study's objective was to determine RE-PACT's feasibility, acceptability, fidelity, and estimated effect size.

Methods

This two-site randomized controlled trial occurred from April 2022-February 2024 in demographically and geographically distinct locations. Caregiver-child pairs were recruited from complex care programs, and children

SUBMITTER: Coller RJ 

PROVIDER: S-EPMC12169566 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature