Genomic analysis and lysogenic conversion of novel RAP44-like phages in Riemerella anatipestifer.

ABSTRACT: Riemerella anatipestifer, an important waterfowl pathogen, causes severe economic losses because of limited prevention and control methods. We aimed to characterize the prophages of R. anatipestifer and explore their role in lysogenic conversion and fitness cost to host bacteria based on the interactive infection of 110 wild-type strains and ATCC 11845. The temperate phages PJA1, PJO17, PJR4, PJL1, and PJX6 were isolated from clinical strains and showed various lytic abilities, high similarity between different Riemerella phages, and stable properties in transmission electron microscopy, temperature sensitivity, and one-step growth curve detection. To study the effects of lysogeny, we developed five lysogenic strains by integrating phages into the genome of JW1, a wild-type and prophage-ab

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12169736 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature